Facilities

• Bioprocessing Research User Facility
• Mouse Genetics Research User Facility
• Dosimetry Applications Research Calibration Laboratory

Bioprocessing Research User Facility

The Bioprocessing Research Facility (BRF) includes laboratories for the investigation of advanced bioprocessing concepts using stirred-tank and columnar bioreactors and a fermentation pilot plant for large-scale batch and columnar experiments. Other research and support laboratories are available on-site.

For more information about equipment and research and development activities, please visit the BRF website at http://www.ct.ornl.gov/ber/userfacility2.htm.

CONTACT
Jonathan R. Mielenz, Manager
Phone: (865) 576-8522
Email: mielenzjr@ornl.gov

Mouse Genetics Research Facility

For over 50 years, the Mouse Genetics Research Facility (MGRF) at Oak Ridge National Laboratory (ORNL) has attracted a highly qualified staff of mouse geneticists and molecular biologists who use its standard and mutant strains of laboratory mice for basic research in analyzing gene function and identifying mouse models of human genetic disease. In May 2004 the MGRF opened a new, 36,000-ft2 vivarium on the main ORNL campus at ORNL. This new vivarium, the William L. and Liane B. Russell Laboratory for Comparative and Functional Genomics, is being operated by Bionetics, Inc., as a specific-pathogen-free barrier facility with a capacity for 60,000 mice. Mouse strains, rederived from the transfer of two-cell stage embryos, are housed in ventilated racks with automated watering systems; basic husbandry is provided by certified technical staff.

For more information, please visit the Mouse Genetics Research Facility website at http://www.ornl.gov/sci/mgrf/index.shtml.

CONTACT
Darla R. Miller
Phone: (865) 574-0858
Email: millerdr@ornl.gov

Dosimetry Applications Research Calibration Laboratory

Oak Ridge National Laboratory's Dosimetry Applications Research Calibration Laboratory (DOSAR CalLab) is managed and operated by the staff of ORNL's Life Sciences Division for personnel dosimetry research, dosimetry intercomparison studies, dosimetry performance test programs, training of health physics personnel, and radiobiology research.

The DOSAR CalLab is a 260 m2 concrete block building consisting primarily of a control room, a 6.1 x 7.0 x 4.3-m gamma irradiation room, a beta/X-ray room which is the same size as the gamma room, and a low-scatter 9.1 x 9.1 x 5.8-m neutron room. The CalLab has been outfitted with track systems in each room for movement of sources or phantoms. These track systems, which are fitted with digital measuring systems for precise source-to-target distance measurements, are suspended from the ceiling and do not interfere with equipment brought into the facility for performing experiments. CalLab space is supplemented by an adjacent building which is available both for storage and for selected low-level irradiations.

For more information, please visit the DOSAR website at http://bio.lsd.ornl.gov/dosar/index.shtml.

CONTACT
James S. Bogard
Phone: (865) 574-5851
Email: bogardjs@ornl.gov